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An Introduction to Medicinal Chemistry
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The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students. Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers. The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques. An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.
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Product details
Paperback: 752 pages
Publisher: Oxford University Press; 4th edition (March 25, 2009)
Language: English
ISBN-10: 0199234477
ISBN-13: 978-0199234479
Product Dimensions:
10.4 x 1.7 x 7.6 inches
Shipping Weight: 3.7 pounds
Average Customer Review:
4.7 out of 5 stars
31 customer reviews
Amazon Best Sellers Rank:
#1,309,364 in Books (See Top 100 in Books)
This text was use in an undergraduate medical chemistry course. Overall, the text is excellent at explaining the development and testing process used in the medical industry to bring new drugs to the market. If you do not have a good background in organic chemistry and possibly biochemistry, I do not recommend purchasing until you have a good understanding of the general concepts within these fields/subjects. The best way to really understand the development process is to see journal articles and other published research to get a feel for how and why certain experiments are performed and understand the FDA approval process. This book provides a good introduction but outside sources similar to described above will greatly supplement this text.
I have never written a review before but this book has become a fixture in my life. It has become dog eared, marked up, highlighted, underlined - the works. To put this in perspective, I have a background and degree in computer science and am in a PhD program doing computational drug design. I had enough undergrad premed to be dangerous and to follow discussions, but my true strength was on the computational side. I bought this book to help me pick up my chemistry and biochemistry and, with all due humility, it worked like a charm. The explanations are clear and beautiful and, if you like this stuff, it's a page turner. Seriously. Yes, it is an introductory text. But man is it a good one. From here I have been able to move on to other graduate texts, contribute equally in my lab on the biochem front, and even had the opportunity to ask some questions of Christopher Lipinski (of Rule of Five fame) at a conference without embarrassing myself. If you are relatively new to drug design or medicinal chemistry or pharmacology and want to come up to speed quickly, and have at least, say, AP high school chemistry or maybe undergrad chemistry, particularly with at least one organic chem class, BUY THIS BOOK. I cannot say it enough. If you are in a position similar to mine, this book is outstanding. In the context of my degree program, maybe even life changing. The single best academic purchase I've made. Sorry to come off like a fan boy, but this book earned it. It's that good.
Very good!
Very clear and accessible introductory text. I didn't have to work very hard to understand what the author was trying to convey.
Very helpful!
Useful book for somebody who is not already in the field or somebody who wants to get involved.Well written.
I like the way this book is organized. Interesting to read, full of the information you want to know about med chem
Very fun reads easily, not much of a detailed textbook though as it is only an very good overview
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